TOPICAL CORTICOSTEROIDS

Intralesional corticosteroid therapy is a procedure where a steroid solution is injected into the skin in order to improve skin appearance and minimize the side effects of skin conditions. The most commonly used steroid in this procedure is triamcinolone.

  • Indications
  • Mechanism of actions
  • Limitations and side effects
This technique is commonly used for removing scars (especially hypertrophic scars and keloids) and a variety of other skin conditions, either alone or in combination with other forms of treatment, often multiple small injections are carried out and you may require more than one session of treatment.
The definite mechanism of corticosteroids is factually unknown; but there are some purposed procedures for explanation like reducing fibroblast proliferation and collagen synthesis and inflammatory factors suppression.
Pain: The procedure is generally well tolerated but injections into certain areas of the body, for example, palms of hands or soles of feet can be more painful.
Bleeding: Small amounts of blood spotting may occur after the injection.
Atrophy: Shrinkage of the tissue at and around the sites of injection may occur due to destruction of subcutaneous fat. This results in a white depressed area, or small scar like areas. The face, genitalia and lips are more susceptible to this than other parts of the body.
Hyper/hypo pigmentation: Changes in pigmentation can occur at and around the sites of injection with either lightening or darkening of skin color. It’s the result of destruction of melanocytes.
Telangiectasia: Infrequently tiny dilated blood vessels or small red spots called purpura may become visible at the injection site.